Collaborative Stage for TNM 7 - Revised 01/21/2010
EsophagusGEJunction
EsophagusGEJunction
C16.0, C16.1, C16.2
- C16.0 Cardia, Esophagogastric junction (EGJ)
- C16.1 Fundus of stomach, proximal 5cm only
- C16.2 Body of stomach, proximal 5cm only
- The cardia/EGJ, and the proximal 5cm of the fundus and body of the stomach have been moved from the Stomach schema and added to Esophagus effective with AJCC TNM 7th Edition. Due to differences in the schemas for Esophagus and Stomach, a new schema was created in CSv2 to accommodate these changes. Since primary site codes C16.0 (gastric cardia), C16.1 (fundus of stomach), and C16.2 (body of stomach) can be assigned to either schema, EGJunction or Stomach, a schema discriminator field is needed for the CS Algorithm to determine which schema to select.
In 7th ed., cancers whose midpoint is in the lower thoracic esophagus, esophagogastric junction, or within the proximal 5 cm of the stomach (cardia) that extend into the esophagogastric junction or esophagus are stage grouped similar to adenocarcinoma of the esophagus. All other cancers with a midpoint in the stomach greater than 5 cm distal to the esophagogastric junction, or those within 5 cm of the esophagogastric junction but not extending into the esophagogastric junction or esophagus, are stage grouped using the gastric cancer staging system.
Anatomic Limits of Cardia:
Cardia: proximal 5 cm of the Stomach
Esophagogastric junction (C16.0): The junction between the esophagus and the stomach epithelium at approximately 40 cm.
Fundus of Stomach (C16.1)
Body of stomach (C16.2)
Effective with AJCC TNM 7th Edition, there are separate stage groupings for squamous cell carcinoma and adenocarcinoma. Since squamous cell carcinoma typically has a poorer prognosis than adenocarcinoma, a tumor of mixed histopathologic type or a type that is not otherwise specified should be classified as squamous cell carcinoma.
Effective with AJCC TNM 7th Edition, histologic grade is required for stage grouping.